Iris

Keeping up with Dementia Research - Monthly Roundups by Iris

Dementia Research news, once a month, in about five minutes: Alzheimer's disease clinical trials, dementia drug approvals, blood biomarkers for dementia, neurodegeneration mechanisms and genetics, dementia risk factors and prevention, and dementia care research. Every story links to its sources.

How to keep up with dementia research

Latest: September 2026

FDA clears PrecivityAD2 for adults as young as 40

  • FDA cleared C2N's PrecivityAD2 for symptomatic adults aged 40 and older, with supporting evidence that it improved primary-care diagnostic accuracy from 65% to 93%:
  • Acadia's remlifanserin Phase 2 RADIANT topline narrowly missed its primary endpoint, met a key secondary endpoint and leaves both Phase 3 studies continuing:
  • A meta-analysis found modest lecanemab-related cognitive benefits alongside a substantially higher risk of ARIA-E, while a real-world cohort showed treatment-associated plasma proteins moving in four different directions:

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