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Keeping up with Protein Design - Monthly Roundups by Iris

Protein Design news, once a month, in about five minutes: de novo protein design, protein structure prediction, generative models for proteins, enzyme and antibody engineering, structural biology and cryo-EM, and protein language models. Every story links to its sources.

How to keep up with protein design

Latest: September 2026

Guo team designs proteins with controllable conformational switching

  • Guo et al. demonstrated de novo proteins with controllable conformational switching and calcium-regulated allostery,
  • DreamFold reported folding-pathway generation up to roughly 30,000 times faster than molecular dynamics,
  • BioMarin and Profluent began a collaboration to generate enzyme-replacement-therapy candidates with protein language models,

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